Anatomical and Physiological Changes


 


Structure and Posture


            According to  (1981) and  (1996) one loses one and half to 3 inches or 1.2 cm. of height every 20 years as aging occurs. Obvious manifestations, which are an interaction of many factors such as age, sex, race, and environment, occur in the fifth decade of life. Long bones take on the appearance of disproportionate size because the stature decreases. Vertebral disks become thin due to dehydration, causing a shortening of the trunk. Many aged persons assume a stooped, forward-bent posture, with hips and knees somewhat flexed and arms bent at the elbows, raising the level of the arms. Posture and structural changes occur primarily because of calcium loss from bone and as a result of atrophic processes of cartilage and muscle. Excessive leaching of calcium from the bone matrix creates the condition called osteoporosis. This type of degeneration is four times more prevalent in women ( 1985), becoming apparent as estrogen declines in older women.


 


Skin, Hair, and Nails


            Epidermal cell renewal time increases by one third after 50 years of age. The normal young adult renews epithelium every 20 days, whereas an older person requires 30 or more days because of diminished mitotic epidermal activity. Because of this slow replacement of epidermal cells, wound healing is approximately 50% slower than at 35 years of age ( 1978). The amount of collagen decreases approximately 1% per year, causing the skin to “give” less under stress and tear more easily ( 1988). The dermis becomes thinner in the absence of subcutaneous fat ( 1983).


            Hair becomes gray because of the decrease in melanin production in hair follicles. Regardless of sex, 50% of the population over 50 years of age has gray or partly gray scalp hair. Body and facial hair becomes gray later. Hair loss is prominent in men, beginning in the second decade for some.


 


Facial Changes


            Facial changes occur as a result of altered subcutaneous fat, dermal thickness, decreased elasticity, and lateral surface compression of underlying muscle contractions. Loss of bone mass, particularly the mandibular bone, accentuates the size of the upper mouth, nose, and forehead. Indented “loss of lip” appearance of the mouth occurs with tooth loss when uncorrected by dentures or other oral prostheses. Eyelids appear swollen as a result of the redistribution of fat deposits. Conversely, eyes that look sunken are the result of the loss of orbital subcutaneous fat. Loss of elasticity accentuates jowls and elongated ears and contributes to the formation of a “double” chin.


 


Loss of Tissue Elasticity


            Tissue elasticity is most easily observed in skin integrity and reflects the progressive, universal, and intrinsic nature of age changes. The aged skin loses resilience and moisture, taking on a characteristic dryness.


 


 


 


Anesthesia in the Elderly


            Many geriatric surgeries are performed as a result of increasing longevity. In geriatric patients there is reduction of cardiovascular, respiratory, renal and liver functions, These in very little functional reserve which is safety margin available to the patient during anesthesia and the post-operative period and contributes to the increased morbidity and mortality. The major risk factors in the elderly are:




  • Poor general condition




  • Severity of co-morbid conditions




  • Major surgery




  • Emergency surgery




Anesthesia should be safe with smooth induction, maintenance and quick reversal without producing any CVS, RS, and CNS complications. The choice of anesthesia depends on the general condition of the patient, the nature of surgical procedure and the experience of the Anesthetist.


 


Type of Anesthesia


           


Regional Anesthesia


            Regional anesthesia is commonly administered in elective surgeries in the elderly. Regional anesthesia involves blockade of major nerve trunks which innervates the site of surgery. The two types of regional anesthesia are spinal and epidural. In spinal anesthesia the drug is injected into the subarachnoid space and in epidural anesthesia the drug is injected into epidural space. In elderly surgery, regional anesthesia is preferred for the following reasons:




  • Advantageous in debilitating respiratory disease patients




  • Reduces bleeding, postoperative respiratory problems and deep vein thrombosis




  • Diminishes stress response and CNS complications




  • Decreases convalescence time and facilities early ambulation




  • Minimizes requirements of postoperative analgesia




  • Reduces mortality 




 


            Disadvantages include:


 




  • Technically difficult




  • Epidural is less reliable




  • Supplemental sedation carries great dangers like air way obstruction, pulmonary aspiration and agitation




 


General Anesthesia


 


Causes of Failure to Breath after General Anesthesia




  • Obstruction of the airways




  • Central sedation from opium drugs or anesthetic agents




  • Hypoxia or hyoercarbia of any cause




  • Persistent neuromuscular blockade




  • Pneumothorax from pleural damage during anesthesia surgery




  • Circulatory failure leading to respiratory arrest




 


 


 



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